- Eade
- Eaglin
- Ealy
- Earl
- Early
- Earthman
- Easley
- Eason
- Eastburn
- Easterling
- Eastman
- Easum
- Eaton
- Eaves
- Ebert
- Ebey
- Echols
- Echt
- Eckelhoff
- Eckels
- Eckford
- Eckles
- Ecrement
- Eddie
- Eddings
- Edgar
- Edge
- Edgington
- Edmiston
- Edmond
- Edmondson
- Edmonson
- Edney
- Edrington
- Edwards
- Efnor
- Egbert
- Eggerson
- Ehrhard
- Eichman
- Eide
- Eidson
- Eiseman
- Elam
- Eldridge
- Eleby
- Elerson
- Elias
- Elion
- Elkins
- Elliot
- Elliott
- Ellis
- Elliston
- Elosua
- Elrod
- Ely
- Emanus
- Embrey
- Embry
- Emerson
- Emigh
- Emmons
- Emory
- Emrich
- Enck
- Endicott
- Enerson
- Engelberg
- England
- English
- Enoch
- Enochs
- Enright
- Eppenger
- Epperson
- Eppinette
- Epstein
- Erb
- Erby
- Erhardt
- Erickson
- Ervin
- Erwin
- Eschbach
- Escue
- Esgro
- Eskridge
- Espinosa
- Essary
- Ester
- Estes
- Etheredge
- Etzel
- Eubank
- Eubanks
- Euell
- Evangelisti
- Evans
- Everett
- Everheart
- Everton
- Ewell
- Ewing
- Exelbierd
- Exum
- Ezekiel
- Ezell